The dairy butter differs by special properties, since it mostly contains milk fat and has high biological value. Currently, in connection with environmental pollution dangerous substances can get in milk products including the dairy butter. They can have harmful effects on the human body. The salts of heavy metals, pesticides, mycotoxins are met more often. 19 samples of the dairy butter with mass fraction of fat 72,5; 79; 82,5 % were studied by safety indices. All the studies were carried out in the specialized laboratories, and the results were confirmed by trials protocols. Standard methods were applied to assess dairy butter samples. It was established that toxic elements, pesticides and mycotoxins were found in all the samples studied but their contents did not exceed permissible levels. In this regard, it is recommended to carefully monitor the raw materials intended for butter production as well as to improve control of safety indices at all stages of the technology of the dairy butter production.